a database of S/T/Y phosphorylation sites
Statistics
:
Instances
42.914
Kinases
299
References
3.657
Sequences
11.224
Substrates
8.698
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Name
Description
Molecular Function
Cellular Component
Biological Process
IL-6R (gp130)
gp130 is shared by members of the IL-6 family
ciliary neurotrophic factor receptor activity
,
ciliary neurotrophic factor receptor binding
,
protein homodimerization activity
,
interleukin-27 receptor activity
extracellular region
,
external side of plasma membrane
,
oncostatin-M receptor complex
,
ciliary neurotrophic factor receptor complex
,
interleukin-6 receptor complex
,
extracellular space
regulation of Notch signaling pathway
,
positive regulation vascular endothelial growth factor production
,
positive regulation of anti-apoptosis
,
response to cytokine stimulus
,
glycogen metabolic process
,
positive regulation of tyrosine phosphorylation of Stat1 protein
,
positive regulation of adaptive immune response
,
positive regulation of osteoblast differentiation
,
positive regulation of tyrosine phosphorylation of Stat3 protein
,
leukemia inhibitory factor signaling pathway
,
negative regulation of interleukin-6-mediated signaling pathway
,
ciliary neurotrophic factor-mediated signaling pathway
,
positive regulation of T cell proliferation
,
interleukin-27-mediated signaling pathway
,
positive regulation of astrocyte differentiation
,
positive regulation of acute inflammatory response
,
positive regulation of cardiac muscle hypertrophy